Glioblastoma

A fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain and spinal cord and has cells that look very different from normal cells. Initial signs may include headaches, personality changes, nausea, and symptoms similar to those of a stroke. Symptoms often worsen rapidly and may progress to unconsciousness. About 3 in 100,000 people develop the disease per year.

Purposeful lead

Purposeful partners with biotech company Biomtech to identify drug repurposing candidates against GBM. After a two-series successful preclinical in-vivo results, a new set of experiments are now scheduled for alternative dosing strategy. Results are anticipated at the end of this year; if successful the company will seek additional funding for a Phase II trial. The company has filed one patent application.

In silico
Post discovery
In vitro
In vivo
Regulatory
Clinical trials